ABSTRACT

Objectives: Demonstrate our early and preliminary experience with the use of small intestinal submucosa [SIS] as a suburethral sling in the treatment of stress urinary incontinence[SUI] in females.

Introduction and Objectives

Health economic analyses are used routinely to evaluate a number of types of healthcare interventions and are required for all new pharmaceuticals by many national and regional health authorities.

ABSTRACT

Introduction: Stress urinary incontinence is associated with substantial economic costs for incontinence management, decrement in health-related quality of life, and a high willingness to pay for incontinence care.

Introduction and Objectives: Women with overactive bladder and other lower urinary tract symptoms (LUTS) may not improve through monotherapy with antimuscarinic agents or alpha-blockers. To evaluate the efficacy and safety of tamsulosin and tamsulosin plus tolterodine in women with lower urinary tract symptoms, we assessed changes of international prostate symptom scores (IPSS), bladder diary variables, and safety and tolerability following 2 different treatments.

Introduction and Objectives: Although there is an accumulation of data that suggest 2-pore domain potassium (K2P) channels are involved in diverse cellular functions such as cell excitability, signal transduction, apoptosis, and abnormal cell proliferation, and thus probably involved in many different physiological and pathophysiological processes, limited data are available for native K2P channel characteristics, including tissue-specific expression patterns and pharmacological properties. Thus, aims of this study were to examine if stretch-activated K2P channels such as TREK1, TREK2, and TRAAK expressed in bladder mucosa and to measure urinary incontinence-associated changes of RNA and protein levels.

ABSTRACT

Introduction and Objectives: Health economic analyses are used routinely to evaluate a number of types of health care interventions and are required for all new pharmaceuticals by many national and regional health authorities. These analyses assess the implications of projected outcomes and costs of a new drug treatment, and are often used as a tool to guide decisions about pharmaceutical development and consumption. As an illustrative example, an overview of the components and construction of an economic model are presented here using the costs and outcomes associated with fesoterodine (FESO), a new antimuscarinic that has been shown to be safe, tolerable, and effective for the management of overactive bladder (OAB) in adults.

ABSTRACT

Introduction and Objectives: Fecal incontinence (FI) is a socially isolating disorder with a prevalence of 6-24% in women with urinary incontinence. The objective of this cross-sectional study is to evaluate the prevalence of FI subtypes (liquid and both liquid and solid stool loss) in women with stress predominant urinary incontinence (UI) and to determine which potential factors (sociodemographic, health status, history, and severity) are associated with FI.

ABSTRACT

Introduction: Pad use per day is a controversial endpoint for measuring urinary incontinence severity. Our objective was to determine if pad use could be used as a proxy measurement assessing patient quality of life after pubovaginal sling surgery (PVS).

ABSTRACT

Introduction and Objectives: Urogenital fistulae in females, when acquired after surgery or obstetric trauma, are associated with significant morbidity and dreadful social and psychological consequences. Successful management of these fistulae demands a high level of skills as well as adherence to basic surgical principles. We review the management of urogenital fistulae at Shifa International Hospital, Islamabad, Pakistan.

ABSTRACT

Introduction and Objectives: The benign prostatic hyperplasia (BPH) is widely spread disease in man over 50. The results of investigation show, that clinical symptoms of BPH are caused by detrusor hypoxia and insufficiency of energetic metabolism due to infravesical obstruction.

Introduction and Objective

Determine if peri- and postoperative outcomes after Burch colposuspension or pubovaginal sling for stress urinary incontinence (SUI) differed with age.

Introduction and Objectives

According to the 3rd International Consultation on Incontinence (2005), few trials have investigated the association between patient characteristics and outcome of physiotherapy intervention for urinary incontinence.

Introduction

Pad use per day is a controversial endpoint for measuring urinary incontinence severity.

Objectives

To describe the characteristic of patients with interstitial cystitis and to determine what proportion of those patients met the ESSIC 2005 (European Society for the Study of IC/PBS (interstitial cystitis/painful bladder syndrome)) definition and how those who met the definition differed from those who did not.

Purpose

Acute urinary retention (AUR) is a serious complication of male with lower urinary tract symptoms (LUTS).

ABSTRACT

Introduction: We hypothesized that women with pelvic organ prolapse (POP) and overt stress urinary incontinence (SUI) would demonstrate less obstruction and retention because of the “release valve” effect of a less competent urethra. To evaluate this, we conducted a prospective supplementary study to the Colpopexy And Urinary Reduction Efforts (CARE) study. We compared voiding parameters and symptoms in 3 groups of women with POP: 1) women with no symptoms of SUI and no urodynamic stress incontinence (USI) during prolapse reduction , 2) women with no SUI symptoms but evidence of USI on reduction testing (occult USI) and 3) women with SUI symptoms (overt SUI).

ABSTRACT

Introduction: To better understand the correlation between non-instrumented uroflowmetry (NIF) and pressure-flow studies (PFS) in women with pelvic organ prolapse (POP), we conducted a prospective supplementary study to the Colpopexy And Urinary Reduction Efforts (CARE) study.

Department of Nursing and Midwifery, University of Southampton, UK.

To compare the performance and cost-effectiveness of the key absorbent product designs to provide a more solid basis for guiding selection and purchase. Also to carry out the first stage in the development of a quality of life (QoL) instrument for measuring the impact of absorbent product use on users' lives.

ABSTRACT

Introduction and Objectives: The aims of the present study were to determine the indications for anti-incontinence surgery and evaluate the efficacy of different methods (combination of anterior colporraphy with TVT, vaginal wall sling (VWS), Raz needle suspension) in preventing postoperative stress urinary incontinence (SUI) in women undergoing surgery for severe urogenital prolapse.

 ABSTRACT

Introduction and Objectives: Cluster analysis is a statistical method for categorizing groups of individuals with similar properties or characteristics. This method is useful for examining the relationship between complex urological problems and other health conditions or lifestyle factors. The method has previously been shown to differentiate men with mixed patterns of voiding and storage symptoms in a large Canadian sample [1]. Assessing symptom co-occurrence can increase understanding of the disease etiology and has patient management implications. We used this method to classify men with storage, voiding, and post-voiding symptoms in the Boston Area Community Health (BACH) Survey [2].