Role of urinary tract infection in bladder cancer: a systematic review and meta-analysis.

We sought to examine the literature reporting the effect of urinary tract infection (UTI) on non-schistosomiasis-related UBC (UBCNS) through a systematic review and meta-analysis.

A predefined study protocol was developed according to PRISMA.

The safety of a mixture of bupivacaine and lidocaine in children after urologic inguinal and scrotal surgery.

Local anesthetic agents such as bupivacaine and lidocaine are commonly used after surgery for pain control. The aim of this prospective study was to evaluate the safety of a mixture of bupivacaine and lidocaine in children who underwent urologic inguinal and scrotal surgery.

Predictive Factors of Contralateral Operation after Initial Pyeloplasty in Children with Antenatally Detected Bilateral Hydronephrosis Due to Ureteropelvic Junction Obstruction.

This study was performed to analyze the predictive factors of a contralateral operation after initial pyeloplasty in patients with antenatally detected bilateral ureteropelvic junction obstruction.

Patients with prenatally diagnosed bilateral ureteropelvic junction obstruction who underwent initial pyeloplasty (aged <12 months at initial pyeloplasty) were offered to participate in the study.

Determinants of urinary catheter removal practices in the pediatric intensive care unit: A survey.

Prolonged use of indwelling catheters is associated with hospital-acquired urinary tract infections (UTIs). Literature is scarce about the factors influencing urinary catheter removal and maintenance in children.

Risk Factors for the Development of Bladder and Bowel Dysfunction - Beyond the Abstract

Bladder and bowel dysfunction (BBD) is increasingly recognized as an entity that has a negative impact on urinary tract health. Since BBD is a known risk factor for recurrent urinary tract infections (UTIs) and potential renal scarring, it is important to understand and recognize factors that place children at risk for BBD. The American Urological Association Vesicoureteral Reflux (VUR) guidelines recommends treatment of BBD before any surgical intervention for VUR is undertaken. Previously risk factors for the development for BBD were not well defined. Female sex was highly associated with BBD in a large multivariable analysis of >2500 patients at risk for UTI, but this study found no association between BBD and reflux. Similarly, overweight children were shown to be less responsive to treatment of BBD, but it was unclear if overweight children were at risk for developing BBD. We sought to identify the risk factors for the development of BBD with a secondary data analysis of two studies (RIVUR and CUTIE) that prospectively measured BBD status with a validated questionnaire, the DVQ score. 

Bilateral Obstructive Uropathy Caused by Congenital Bladder Diverticulum Presenting as Hypertensive Retinopathy.

A congenital bladder diverticulum (CBD) is caused by inherent muscular weakness instead of obstruction of the bladder outlet. The major clinical conditions are recurrent urinary tract infection (UTI) and voiding dysfunction.

Diagnostic accuracy of urinary biomarkers in infants younger than 3 months with urinary tract infection.

The aim of this study was to evaluate the diagnostic accuracy of urinary biomarkers, such as neutrophil gelatinase-associated lipocalin (uNGAL) and β-2 microglobulin (uB2MG), in early detection of urinary tract infection (UTI) in infants aged <3 months with fever.

Bladder Re-Augmentation in Classic Bladder Exstrophy: Risk Factors and Prevention.

To characterize the causes of re-augmentation in patients with classic bladder exstrophy.

A prospectively-maintained institutional database of 1327 exstrophy-epispadias complex patients was reviewed for CBE patients who have undergone more than one AC procedure.

Primary female epispadias: Perineal approach or Kelly repair?

Primary female epispadias encompasses a spectrum of disease, presenting with a variable degree of incontinence. We hypothesized that although perineal urethrocervicoplasty can be a successful first-line procedure in patients with normal bladder, a more radical reconstruction was necessary to achieve continence in cases lying at the most severe end of the spectrum.

Etiology and antimicrobial resistance patterns in pediatrics with urinary tract infections.

Urinary tract infections (UTIs) are one of most common pediatric infections. The aim of this study was to investigate the etiology and antimicrobial resistance patterns of hospitalized children in our center.

Management and Outcomes of Childhood Renal Artery Stenosis and Middle Aortic Syndrome.

Renal artery stenosis (RAS) in isolation or in conjunction with middle aortic syndrome (MAS), are important vascular causes of childhood hypertension. Few longitudinal studies have assessed the risk of surgical or endovascular intervention, and outcomes by etiology or extent of vascular disease.

Early versus delayed closure of bladder exstrophy: A National Surgical Quality Improvement Program Pediatric analysis.

Delayed closure of bladder exstrophy has become more popular; however, there is limited the evidence of its success. Existing literature focuses on intermediate and long-term outcomes, and short-term postoperative outcomes are limited by the small number of cases and varying follow-up methods.

Pediatric pelvic fracture urethral distraction defect causing complete urethrovaginal avulsion.

Pelvic fracture with urethral injury in girls is an uncommon entity that is usually associated with concomitant vaginal lacerations. Management options vary from immediate exploration and urethral anastomosis to delayed urethroplasty.

A homozygous missense variant in VWA2, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux.

Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause (40-50%) of chronic kidney disease (CKD) in children. About 40 monogenic causes of CAKUT have so far been discovered.

Long-term outcome of one-step kidney transplantation and bladder augmentation procedure in pediatric patients.

Guidelines for bladder augmentation (BA) in kidney transplant (KT) recipients are not well-defined. In our center, simultaneous BA with KT (BA-KT) is performed. We assessed transplantation outcomes of this unique extensive procedure.

A critical review of recent clinical practice guidelines for pediatric urinary tract infection.

Concerns regarding the quality, credibility, and applicability of recently published pediatric urinary tract infection (UTI) clinical practice guidelines have been raised due to the inconsistencies of recommendations between them.

Normal pelvic ultrasound or MRI does not rule out neoplasm in patients with gonadal dysgenesis and Y chromosome material.

Patients with gonadal dysgenesis (GD) with a Y chromosome have an increased risk of gonadal neoplasm. Few data exist on the ability of imaging to detect malignancy in intra-abdominal gonads in these patients.

Childhood disease burden: Is father to blame?: Beyond the Abstract

Poor lifestyles and paternal preconception health are strong determinants of health of the offspring. During the last decade, there has been a decline in human semen quality and sperm health. From conception of father, adverse childhood events, psychological stress, and poor social habits impact sperm epigenome and may lead to increased risk of genetic and epigenetic diseases in the offspring.

Accuracy of cystatin C for the detection of abnormal renal function in children undergoing chemotherapy for malignancy: a systematic review using individual patient data.

We conducted a systematic review and individual patient data (IPD) meta-analysis to examine the utility of cystatin C for evaluation of glomerular function in children with cancer.

Eligible studies evaluated the accuracy of cystatin C for detecting poor renal function in children undergoing chemotherapy.

Aspects of urinary tract infections and antimicrobial resistance in hospitalized urology patients in Asia: 10-Year results of the Global Prevalence Study of Infections in Urology (GPIU).

To assess Asian data from Global Prevalence Study on Infections in Urology (GPIU study) which has been performed more than 10 years.

Seventeen Asian countries participated in the GPIU study between 2004 and 2013.