These results confirm the evidence used to compile the AJCC TNM classification, in which prostatic stromal invasion alone was categorized as pT4 disease. The study highlights the importance of careful pathologic evaluation to differentiate prostatic stromal invasion from ductal/urothelial invasion. Although this clinical phenomenon has been well described, the biology behind prostatic stromal invasion remains elusive. Future studies assessing the molecular features driving prostatic stromal spread would be of interest.
Presented by: Marco Moschini MD
Written By: Roger Li MD Urologic Oncology Fellow, Department of Urology, UT MD Anderson Cancer Center, Houston, TX
Ashish M. Kamat MD Wayne B. Duddlesten Professor, Department of Urology, UT MD Anderson Cancer Center, Houston TX
at the 2017 AUA Annual Meeting - May 12 - 16, 2017 – Boston, Massachusetts, USA