Glucocorticoids Articles


  • Addison's disease in antiphospholipid syndrome: a rare complication.

    Addison's disease (AD) is the most common endocrine manifestation of antiphospholipid syndrome (APS), but it remains a very rare complication of the syndrome. It is caused by adrenal venous thrombosis and consequent hemorrhagic infarction or by spontaneous (without thrombosis) adrenal hemorrhage, usually occurring after surgery or anticoagulant therapy.

    Published December 2, 2018
  • Glucocorticoid receptor beta increases migration of human bladder cancer cells.

    Bladder cancer is observed worldwide having been associated with a host of environmental and lifestyle risk factors. Recent investigations on anti-inflammatory glucocorticoid signaling point to a pathway that may impact bladder cancer.

    Published April 2, 2016
  • Sweet-P inhibition of glucocorticoid receptor β as a potential cancer therapy.

    The need for the development of new cancer therapies and push for the design of new targeting techniques is on the rise, and would be useful for cancers that are resistant to current drug treatments.

    Published July 31, 2016
  • The Role of Glucocorticoid Receptor Signaling in Bladder Cancer Progression.

    Previous preclinical studies have indicated that the activation of glucocorticoid receptor signaling results in inhibition of the growth of various types of tumors. Indeed, several glucocorticoids, such as dexamethasone and prednisone, have been prescribed for the treatment of, for example, hematological malignancies and castration-resistant prostate cancer.

    Published December 12, 2018

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