PATIENTS AND METHODS: In a series of 270 sexually active men with localized prostate cancer treated with brachytherapy (permanent implants of Iode 125) at the Institute Claudius Regaud between 2000 and 2006, mean age 65 years (43-80), four patients spontaneously expressed their interest in the preservation of fertility and had an andrological evaluation.
RESULTS: Four patients were aged 43, 48, 57 and 61years, all working (including two businessmen), their partner was aged respectively 42, 37, 47 and 38years. All four had a post-treatment semen analysis (done over a year after brachytherapy) rich in spermatozoa, with moderate asthenospermia, the main anomaly being severe hypospermia. These spermiograms were nonetheless consistent with the occurrence of spontaneous pregnancy (occurrence of miscarriage in the patient 1).
CONCLUSION: There is an interest in applying to men with prostate cancer their position on fertility in order to inform them about the morbidity of various treatments, options for fertility preservation, and the need to continue a contraception after brachytherapy if the partner is not menopausal.
Written by:
Delaunay B, Delannes M, Bachaud JM, Bouaziz M, Salloum A, Thoulouzan M, Soulié M, Plante P, Huyghe E. Are you the author?
Département d'urologie et d'andrologie, CHU Rangueil, 1, avenue J.-Poulhes, TSA 50032, 31059 Toulouse cedex 9, France.
Reference: Prog Urol. 2012 Jan;22(1):53-7.
doi: 10.1016/j.purol.2011.06.001
PubMed Abstract
PMID: 22196006
Article in French.
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