From the Editor

From the Desk of the Editor: Increasing incidence of metastatic prostate cancer in the United States

Stephen Freedland
March 29, 2017

PSA screening is the backbone of early prostate cancer detection in the United States and increasingly in other parts of the world too. Due to concerns about over-detection and over-treatment of indolent disease (i.e. harms), PSA screening is controversial, despite level 1 evidence that screening vs. no screening can reduce the risk of death from prostate cancer (i.e. benefits).


stephen j freedland

Stephen J. Freedland, MD

Stephen J. Freedland, MD, is director of the Center for Integrated Research in Cancer and Lifestyle and co-director of the Cancer Genetics and Prevention Program and Associate Director for Faculty Development at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute. He is also a faculty physician in the Division of Urology within the Department of Surgery at Cedars-Sinai. He has served on numerous American Urological Association guideline panels for prostate cancer and co-chaired a prostate cancer guideline panel for the American Society of Clinical Oncology.

Dr. Freedland's clinical area of expertise focuses on urological diseases, particularly benign prostatic hyperplasia and prostate cancer. His approach toward cancer prevention and awareness focuses on treating the whole patient, not just the disease, by combining traditional Western medicine with complementary holistic interventions. His research interests include investigations on urological diseases and the role of diet, lifestyle and obesity in prostate cancer development and progression, as well as prostate cancer among racial groups and risk stratification for men with prostate cancer.

PCAN: March 2017

Increasing incidence of metastatic prostate cancer in the United States (2004–2013).

Changes in prostate cancer screening practices in the United States have led to recent declines in overall incidence, but it is unknown whether relaxed screening has led to changes in the incidence of advanced and metastatic prostate cancer at diagnosis.
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