Clinical Trials

169 results for Prostate Cancer


Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

  • Condition: Prostate Cancer
  • Study ID: NCT01961713
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A Pilot Study of Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (13C) to Detect High Grade Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Drug: Pyruvate (13C)
  • Study ID: NCT02526368
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The UCLA ASCAP Project is an Observational, Longitudinal, and Open-ended Study Aimed at Establishing a Structured Program of Non-interventional Follow-up for Localized Prostate Cancer.

  • Condition: Prostate Cancer
  • Intervention: Other: Active surveillance
  • Study ID: NCT00949819
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Primary Radical Prostatectomy Versus Primary Radiotherapy for Locally Advanced Prostate Cancer: an Open Randomized Clinical Trial

  • Condition: Prostatic Neoplasms
  • Intervention: Procedure: Prostatectomy/Surgery, Other: Radiotherapy with adjuvant androgen deprivation therapy
  • Study ID: NCT02102477
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Safety and Early Efficacy of Radical Prostatectomy for Newly Diagnosed Very High Risk Locally Advanced and Oligometastatic Prostate Cancer - a Prospective Single Center Phase I/II Study

  • Condition: Locally Advanced and Metastatic Prostate Cancer
  • Intervention: Procedure: Radical prostatectomy
  • Study ID: NCT02971358
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Phase III Study of Image Guided Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Adenocarcinoma of the Prostate

  • Condition: Prostate Cancer
  • Intervention: Radiation: Radiation, Drug: Androgen Suppression Therapy
  • Study ID: NCT01492972
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Local Treatment With Radical Prostatectomy (RP) for Newly-diagnosed Metastatic Prostate Cancer (mPCa).

  • Condition: Prostatic Neoplasms, Neoplasm Metastasis
  • Study ID: NCT02138721
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Collection of Blood From Patients With Prostate Cancer

  • Condition: Prostatic Neoplasms
  • Study ID: NCT00923221
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Canary Prostate Active Surveillance Study

  • Condition: Prostatic Neoplasms
  • Study ID: NCT00756665
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[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Drug: [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone
  • Study ID: NCT00588185
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Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene and Characterization of the Predisposition to Renal Cancer

  • Condition: Renal Tumor Histology, Cutaneous Leiomyomatosis, Kidney Cancer
  • Study ID: NCT00050752
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Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

  • Condition: Malignant Neoplasms, Hereditary Neoplastic Syndromes, Kidney Cancer, Renal Cancer
  • Study ID: NCT00026884
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Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy

  • Condition: Prostate Cancer
  • Intervention: Radiation: IMRT to 45 Gy; prostate bed proton boost of 21.6 CGE, Radiation: Proton (prostate bed) to 70.2 CGE, Radiation: IMRT to 45 Gy; proton boost to prostate bed to 25.2 CGE, Radiation: Proton to 66.6 CGE
  • Study ID: NCT00969111
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Collection of Blood From Patients With Cancer for Analysis of Genetic Differences in Drug Disposition

  • Condition: Prostate Cancer, Breast Cancer, Lung Cancer, Ovarian Cancer, Lymphoma
  • Study ID: NCT01441089
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Biospecimen Acquisition From Human Subjects

  • Condition: Prostate Cancer, Breast Cancer, Colon Cancer, Lung Cancer, Liver Cancer
  • Study ID: NCT00034216
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HDR Monotherapy for Prostate Cancer: A Feasibility Study of Focal Radiotherapy Yields

  • Condition: Prostate Cancer
  • Intervention: Radiation: targeted focal HDR brachytherapy, Radiation: Whole-gland HDR Brachytherapy
  • Study ID: NCT02918253
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Phase II Study: [18F]DCFPyL PET/MRI for Personalizing Prostate Cancer Subclinical Metastatic Ablative MR-guided Radiotherapy (MRgRT)

  • Condition: Post Prostatectomy
  • Study ID: NCT03160794
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Prostate Cancer Outcomes: An International Registry to Improve Outcomes in Men With Advanced Prostate Cancer (IRONMAN)

  • Condition: Prostate Cancer
  • Intervention: Other: Standard of Care
  • Study ID: NCT03151629
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A Randomized Pilot Study Comparing High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy in Localized Prostate Cancer

  • Condition: Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8, Stage IIC Prostate Cancer AJCC v8
  • Intervention: Radiation: High-Dose Rate Brachytherapy, Other: Quality-of-Life Assessment, Other: Questionnaire Administration, Procedure: Stereotactic Ablative Radiotherapy
  • Study ID: NCT04253483
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Parallel Phase III Randomized Trials of Genomic-Risk Stratified Unfavorable Intermediate Risk Prostate Cancer: De-Intensification and Intensification Clinical Trial Evaluation (GUIDANCE)

  • Condition: Prostate Adenocarcinoma
  • Study ID: NCT05050084
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Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR): A Randomized Multi-center Study for Men With Newly Diagnosed Favorable Risk Prostate Cancer

  • Condition: Prostate Cancer
  • Study ID: NCT04396808
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Tolerability of Concurrent EBRT + Lu-PSMA for Node-positive Prostate Cancer (PROQURE-1)

  • Condition: Prostatic Neoplasm
  • Study ID: NCT05162573
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A Phase 2 Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With BRCA1/2 Gene Alterations (NePtune)

  • Condition: Prostate Cancer, BRCA1 Mutation, BRCA2 Mutation, Prostatic Adenocarcinoma, High-Risk Cancer
  • Study ID: NCT05498272
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Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy: A Prospective, Single-arm, Multi-center, Blinded-review, Phase 3 Diagnostic Performance Study

  • Condition: Prostate Cancer, Prostatic Neoplasms
  • Study ID: NCT06056830
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A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine M9241 in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy

  • Condition: Cancer Of Prostate
  • Study ID: NCT05361798
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Pilot Clinical Trial of Neoadjuvant SGLT2 Inhibition in High-Risk Localized Prostate Cancer

  • Condition: Prostate Cancer, Cancer of Prostate
  • Study ID: NCT04887935
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A Phase 2 Study of Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (13C) in Patients With Prostate Cancer on Active Surveillance

  • Condition: Prostate Adenocarcinoma
  • Intervention: Drug: Hyperpolarized Carbon C 13 Pyruvate, Procedure: Magnetic Resonance Spectroscopic Imaging, Procedure: MRI Ultrasound Fusion Guided Biopsy
  • Study ID: NCT03933670
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PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

  • Condition: Prostate Cancer
  • Study ID: NCT04995198
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Phase II Study of Talazoparib With Androgen Deprivation Therapy and Abiraterone in Castration Sensitive Prostate Cancer

  • Condition: Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
  • Study ID: NCT04734730
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A Phase 1 Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

  • Condition: Prostatic Neoplasms, Adenocarcinoma
  • Study ID: NCT04644770
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Nivolumab as a Non-Castrating Therapy for MMR-deficient and CDK12- Altered Prostate Cancer With PSA Recurrence After Local Therapy

  • Condition: Prostate Cancer, Recurrent Prostate Cancer
  • Intervention: Drug: Nivolumab
  • Study ID: NCT04019964
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An Observational Study of Darolutamide in Addition to Standard Androgen Deprivation Therapy and Docetaxel in Patients With Low-volume Metastatic Hormone-sensitive Prostate Cancer

  • Condition: Metastatic Hormone-sensitive Prostate Cancer (mHSPC), Low-volume Metastasis
  • Study ID: NCT06661122
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APPROACH : Multimodal Approach in Patients With mHSPC. A Pragmatic Randomized Trial of Apalutamide Plus Androgen Deprivation Therapy (APA-ADT) Versus APA-ADT Plus Local Treatment. A Meet-URO 29 Study

  • Condition: Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
  • Study ID: NCT05649943
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A Multi-center, Randomized, Open-label Clinical Trial Comparing a 6-month vs Long-term Course of Rezvilutamide With ADT Plus Chemotherapy in High Tumor Burden mHSPC

  • Condition: Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
  • Study ID: NCT05956639
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Understanding the Interaction Between Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression

  • Condition: Prostate Adenocarcinoma, Prostate Cancer, Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
  • Study ID: NCT05683964
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Randomized Controlled Study on the Efficacy and Safety of Intermittent Darolutamide Treatment in the Triple Therapy of Metastatic Hormone Sensitive Prostate Cancer

  • Condition: Metastatic Prostate Cancer, Intermitent Anti-androgen Therapy
  • Study ID: NCT06177015
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Exploratory Study on the Efficacy and Safety of Triple Therapy (ADT + Darolutamide + Docetaxel Chemotherapy) Combined With Transrectal High-Intensity Focused Ultrasound Focal Therapy in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) With High Tumor

  • Condition: Prostate Cancer
  • Study ID: NCT07172685
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Evaluating the Efficacy and Safety of Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer

  • Condition: Metastatic Prostate Cancer, Therapy, Directly Observed
  • Study ID: NCT06350825
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24 Gy in One Fraction Urethral-sparing "High-Dose-Rate Like" Stereotactic Body RadioTherapy for Prostate Cancer: a Single-center Non-randomized Prospective Clinical Study (PRO-FAST)

  • Condition: Localized Prostate Carcinoma
  • Study ID: NCT05936736
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Multi-omic Approach to Study High Dose Rate (HDR) Brachytherapy for Favorable Risk and Low Tier Intermediate Risk Prostate Cancer

  • Condition: Localized Prostate Carcinoma
  • Study ID: NCT06200974
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Effectiveness of Focal Therapy in Men With Prostate Cancer

  • Condition: Prostate Cancer, Prostate Neoplasm
  • Study ID: NCT06223295
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Post-marketing Clinical Study of Transrectal High-intensity Focused Ultrasound for Localized Prostate Cancer

  • Condition: Localized Prostate Cancer
  • Study ID: NCT06362577
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WATER IV Prostate Cancer: Aquablation Versus Radical Prostatectomy for the Treatment of Localized Prostate Cancer

  • Condition: Localized Prostate Cancer
  • Study ID: NCT06651632
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A Randomized Phase III Clinical Trial for the Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

  • Condition: Prostate Cancer (Adenocarcinoma)
  • Study ID: NCT06592924
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Open-label Clinical Phase 1/2 Study to Assess the Safety and Efficacy of the SpectraCure P18 System and Verteporfin for Injection for the Treatment of Primary Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Study ID: NCT06807359
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Phase II Trial of 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

  • Condition: Localized Prostate Cancer
  • Study ID: NCT05155046
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Two-fraction High Dose Rate Brachytherapy as Monotherapy Delivered Three Hours Apart in Localized Prostate Cancer: A Pilot Study

  • Condition: Prostate Adenocarcinoma, Localized Prostate Carcinoma
  • Study ID: NCT05665738
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PSMA-Guided Ablation of the Prostate: A Multicenter Randomized Controlled Trial

  • Condition: Prostate Cancer, Localized Prostate Carcinoma
  • Study ID: NCT06003556
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Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)

  • Condition: Prostate Adenocarcinoma, Localized Prostate Carcinoma
  • Study ID: NCT06238713
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Safety and Efficacy Study of Hypofractionated Radiotherapy for Localized Prostate Cancer: a Single-arm Clinical Trial

  • Condition: Localized Prostate Cancer
  • Study ID: NCT06325774
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