A Randomized Clinical Trial Comparing the Efficacy of MRI Versus PSA for Prostate Cancer Screening: The MVP Study (MRI vs PSA)


Condition: Prostate Cancer

Study Type: Interventional

Clinical Trials Identifier NCT 8-digits: NCT02799303

Sponsor: Sunnybrook Health Sciences Centre

Eligibility:

  • Age: minimum 50 Years maximum N/A
  • Gender: Male

Inclusion Criteria:

  • age greater than or equal to 50 years old
  • life expectancy greater than or equal to 10 years, according to the clinical judgement of study investigators

Exclusion Criteria:

  • history of previous prostate biopsy
  • PSA level measurement within 3 years of recruitment date
  • abnormal digital rectal examination of the prostate consistent with prostate cancer
  • history of prostate cancer in one or more first-degree relatives diagnosed at less than 50 years of age
  • lower urinary tract voiding symptoms (IPSS greater than or equal to 8)
  • prior or current use of 5-alpha reductase inhibitor medications (finasteride or dutasteride)
  • patient unable to communicate in English in order to give proper informed consent
  • claustrophobia or other medical indication which would preclude MRI
  • any medical condition which, in the opinion of the investigator, might interfere with the evaluation of the study objectives

View trial on ClinicalTrials.gov