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- In this discussion, Alicia Morgans and Ashley Ross discuss men in the adjuvant setting with the highest risk of prostate cancer metastasis by genomic stratification. They focus their discussion on Decipher molecular testing after prostatectomy and the Phase III ERADICATE study. The ERADICATE trial was presented at this year's ASCO meeting. Biographies: Ashley Ross, MD, Ph.D., Associate Professor,...
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- Lauren Cooley joins Alicia Morgans for a discussion on gender differences in bladder cancer. Men are far more likely to be diagnosed with bladder cancer compared to women. Yet when women are diagnosed with bladder cancer, they are usually older and their disease is more advanced. Dr. Cooley explains how her research uses a mouse model to explore potential genetic and immunologic differences in the...
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- In this conversation, Sam Chang invites Sima Porten to highlight her 2022 AUA presentation, part of the Society of Urologic Oncology (SUO) session where she presented on Adjuvant Therapy after Nephroureterectomy for High-Risk Upper Tract Urothelial Carcinoma (UTUC). Drs. Porten and Chang and Dr. Porten discuss risk stratification in UTUC, immunotherapy as a treatment option now in the adjuvant set...
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- Daniel Lin joins Alicia Morgans in highlighting a guideline-directed practical course on how to use genomics in clinical practice. Dr. Lin was part of the instructional course faculty at the AUA annual meeting. The learning objectives of this course include a discussion on the research studies that led to the approval of genomic testing for prostate cancer, ordering appropriate genomic testing bas...
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- Oliver Sartor joins Alicia Morgans in a brief discussion on the Updates to the NCCN Guidelines for PSMA PET Imaging for Prostate Cancer and how we can think about selecting patients for treatment with Lutetium-177–PSMA-617 using a PSMA PET scans. Biographies: A. Oliver Sartor, MD, Professor of Medicine and Medical Director, Tulane Cancer Center; C. E. and Bernadine Laborde Professor of Cancer Rese...
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- Alicia Morgans is joined by Seth Lerner and discuss his State-of-the-Art Lecture on Bacillus Calmette–Guérin (BCG) unresponsive disease in non-muscle-invasive bladder cancer. They discuss the FDA’s guidance in terms of clinical trial design in the BCG-unresponsive disease space and recap where the treatment landscape is now and what is on the horizon as far as molecular subtypes and predictive bio...
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- Jason Hafron and Katie Murray join Ashley Ross in a conversation on the treatment of unfavorable intermediate-risk prostate cancer and the value of the genomic classifier useful in guiding treatment considerations. Biographies: Jason Hafron, MD, Associate Professor of Urology, The William Beaumont School of Medicine, Oakland University, Director of Robotic Surgery, Beaumont Hospital Royal Oak, Aub...
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- Zach Klaassen joins Alicia Morgans in discussing an underestimated topic of mental health and its effects on patients with genitourinary cancers. Drs. Klaassen and Morgans discuss hypothesis-generating population-level data in this landscape and talk through the importance of supporting these patients and using what Dr. Klaassen refers to as clinical intuition and asking follow-up questions when s...
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- Neal Shore joins Alicia Morgans to discuss pioneering work on establishing the importance of multidisciplinary teams in the management of urologic oncology patients. This was a plenary presentation at the AUA led by Leonard Gomella and Neal Shore and Michael Cookson as panelists. They discussed the importance of a collaborative approach to optimizing patient care. Drs. Morgans and Shore also highl...
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- James Eastham and Stephen Boorjian join Alicia Morgans in a conversation on AUA Guidelines focused on localized prostate cancer. The guidelines provide a framework to have a conversation with a patient about their individual situation involving risk assessment, not only from the cancer standpoint but also from the treatment standpoint. These guidelines provide the framework of what physicians shou...
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