Adrenal Disease

Adrenal Oncocytoma Presenting as Cushing Syndrome: A Rare Clinical Entity


A 15-year-old girl presented with rapid weight gain over a couple of months, depression, and suicidal tendencies. On subsequent evaluation she was found to have Cushingoid features such as centripetal obesity, hirsutism, moon facies, irregular menstrual cycles, and mood disorders. Her blood biochemistry showed raised basal serum cortisol levels and was positive for low and high dexamethasone suppression tests. An ultrasound of the abdomen and later a 64-slice multi-detector computed tomography (MDCT) of the abdomen confirmed an enhanced right-sided adrenal tumor approximately 32 mm x 27 mm x 25 mm.

The patient was subjected to open adrenalectomy, and subsequent histopathology revealed adrenal oncocytoma. Postoperative recovery was uneventful. Her serum cortisol done on the eighth postoperative day showed a normal value. Herein we report a rare case of adrenal oncocytic adenoma presenting with Cushing syndrome.

 Shajidul Mazumder, Rajeev T Puthenveetil, Bikash Bawri, Debanga Sarma, Sasanka Barua, Saumar J Baruah

Submitted April 9, 2012 - Accepted for Publication May 17, 2012

 KEYWORDS: Oncocytoma, Cushing syndrome, adrenal

CORRESPONDENCE: Shajidul Mazumder, MCh Trainee, Department of Urology, Gauhati Medical College and Hospital, Guwahati 32, Assam, India ()

CITATIONUroToday Int J. 2012 October;5(5):art 57.