Pseudocapsule Articles

To assess the characteristics of pseudocapsule (PC) in localized renal cell carcinoma (RCC) by analyzing the rates of completeness of PC and pseudocapsular invasion and clinical and pathological risk factors of it.

Tumor behavior is intricately dependent on the oncogenic properties of cancer cells and their multi-cellular interactions. To understand these dependencies within the wider microenvironment, we studied over 270,000 single-cell transcriptomes and 100 microdissected whole exomes from 12 patients with kidney tumors, prior to validation using spatial transcriptomics.

The aim of this study is to evaluate histological changes in tumor-parenchymal interface in clear cell renal cell carcinoma (ccRCC) after neoadjuvant axitinib treatment.

We obtained clinical and pathology materials from 23 ccRCC patients treated with neoadjuvant axitinib in a phase II clinical trial, and from 23 matched patients with ccRCC that had upfront surgery.