Partial Volume Correction Articles

Purpose: To determine the effect of smooth filter and partial volume correction (PVC) method on measured prostate-specific membrane antigen (PSMA) activity in small metastatic lesions and to determine the impact of these changes on the molecular imaging (mi) PSMA scoring.

Accurate quantification of tracer uptake in small tumors using positron emission tomography (PET) is hampered by partial volume effects as well as by methods of volume of interest (VOI) delineation.

(18)F-Fluoride PET-CT offers the opportunity for accurate skeletal metastasis staging compared to conventional imaging methods. (18)F-Fluoride is a bone specific tracer whose uptake depends on osteoblastic activity.