Immune Cells Articles


  • Ageing and inflammation in the male reproductive tract.

    Ageing is usually characterised by a mild chronic proinflammatory state. Despite the tight association between both processes, the phenomenon has recently been termed inflammageing. Inflammation in the male reproductive tract is frequently linked with bacterial or virus infections but also with a broad range of noninfectious processes.

    Published May 19, 2018
  • Differences of the immune cell landscape between normal and tumor tissue in human prostate.

    Over the past few decades, immunological checkpoint therapy has been an increasingly prominent strategy in the treatment of tumors, including prostate cancer (PC). There are few systematic studies of the phenotypic of tumor-infiltrating immune cells in PC tissues.

    Published June 7, 2019
  • Immune Cells Act as Promising Targets for the Treatment of Bone Metastasis.

    Bone metastasis is a common complication of certain types of cancer, and unfortunately, it is still incurable to date. Immune system is a major defence against tumor cells and bone metastasis. However, the immunodeficient mouse models are widely used in most researches of bone metastasis, thereby excluding the regulatory roles of the immune system in bone metastasis.

    Published June 12, 2017
  • Immune Infiltration and Prostate Cancer.

    It is becoming increasingly clear that inflammation influences prostate cancer (PCa) development and that immune cells are among the primary drivers of this effect. This information has launched numerous clinical trials testing immunotherapy drugs in PCa patients.

    Published September 10, 2015
  • Obesity, Inflammation, and Prostate Cancer.

    The prevalence of obesity is increasing in the world, and obesity-induced disease, insulin-resistance, cardiovascular disease, and malignancies are becoming a problem. Epidemiological studies have shown that obesity is associated with advanced prostate cancer and that obese men with prostate cancer have a poorer prognosis.

    Published February 13, 2019
  • Transcriptomic analysis of the tumor microenvironment to guide prognosis and immunotherapies.

    Tumors are highly heterogeneous tissues where malignant cells are surrounded by and interact with a complex tumor microenvironment (TME), notably composed of a wide variety of immune cells, as well as vessels and fibroblasts.

    Published September 12, 2017