CAV1 Articles

SAN DIEGO, CA USA (UroToday.com) - Patients at high suspicion for prostate cancer, but a negative prostate needle biopsy, pose a difficult diagnostic dilemma and often require additional radiographic, laboratory, and imaging-guided interventions to arrive at an acceptable diagnosis and treatment plan.

Caveolin-1 (CAV1) has been identified to be up-regulated in many cancers, including clear cell renal cell carcinoma (ccRCC). However, its potential function is still unclear in ccRCC. In this study, we demonstrated that CAV1 was frequently overexpressed in renal cell carcinoma tissues and cells, and was significantly associated with various clinicopathological parameters.