Alpha-1 Blocker Articles

To investigate the efficacy of two α1-blockers with different affinity for α1 adrenoceptor subtypes, silodosin and naftopidil, in the treatment of benign prostatic enlargement (BPE) complicated by overactive bladder (OAB).

We evaluated long-term efficacy and safety of a combination therapy (CT) with an anticholinergic agent and an α1-blocker for patients with benign prostatic enlargement (BPE) complaining of voiding and overactive bladder (OAB) symptoms, in comparison with those of α1-blocker monotherapy (MT), by conducting a urodynamic study (UDS).

OBJECTIVE - To investigate the correlation between testosterone levels and Lower urinary tract symptoms (LUTS) and bladder outlet obstruction (BOO), to evaluate the change in testosterone secretion during treatment for LUTS, and to determine the factors that influence testosterone secretion.