Clear Cell Renal Cell Carcinoma with Intratumoral Granulomatous Reaction: A Case Report and Review of the Literature

Granulomatous reaction associated with clear cell renal cell carcinoma (CCRCC) is a rare finding, and only a few cases have been described in the literature. It is postulated to occur due to cancer-related antigenic factors such as cancer cells themselves or soluble tumor antigens shed into the blood. Herein, we describe a case of a 56-year-old male patient diagnosed with CCRCC with intratumoral granulomatous inflammation.

Journal of pathology and translational medicine. 2017 Mar 14 [Epub ahead of print]

Hayeon Kim, Jong Wook Kim, Aeree Kim, Hyeyoon Chang

Department of Pathology, Korea University Guro Hospital, Seoul, Korea., Department of Urology, Korea University Guro Hospital, Seoul, Korea.