BERKELEY, CA (UroToday.com) - This is the first case report of pneumocystis pneumonia (PCP) associated with everolimus therapy for renal cell carcinoma (RCC).
At the patient’s initial visit, we suspected the presence of everolimus-induced interstitial lung disease (ILD) based on chest CT scan findings (Figure 1) because everolimus can induce ILD with a high frequency. However, further examinations demonstrated that the pneumonitis was PCP.
Although less common than ILD, PCP may occur in patients receiving everolimus therapy. There is a risk of misdiagnosis of pneumonitis in patients receiving everolimus therapy when they are assessed solely by the results of chest images.
|Figure 1. Click to enlarge|
Yoshinobu Saito, MD, PhD as part of Beyond the Abstract on UroToday.com. This initiative offers a method of publishing for the professional urology community. Authors are given an opportunity to expand on the circumstances, limitations etc... of their research by referencing the published abstract.
Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan