Tumor metastasis to the oral cavity is rare and is usually an indication of late-stage disease and poor prognosis. While, there are reports of renal cell carcinoma (RCC) metastatic to oral cavity, vast majority of them are to the jaw. Herein, we present a case of a 78-year-old woman with RCC metastasis limited to the oral soft tissue without any bone involvement. As the lesion solely involved maxillary gingiva, it clinically mimicked that of a pyogenic granuloma, which is a reactive, nonneoplastic condition. This case was further complicated as the patient was unaware of primary cancer and appeared to be in good physical health. Her oral metastasis marked the initial manifestation of an otherwise silent primary renal cancer.
Journal of oral and maxillofacial pathology : JOMFP. 2018 Jan [Epub]
Daria Vasilyeva, Scott M Peters, Elizabeth M Philipone, Angela J Yoon
Division of Oral and Maxillofacial Pathology, Columbia University Medical Center, New York, USA.