Radiation therapy may result in urethral strictures from vascular damage. Most radiation-induced urethral strictures occur in the bulbomembranous junction, and urinary incontinence may result as a consequence of treatment. Radiation therapy may compromise reconstruction due to poor tissue healing and radionecrosis. Excision and primary anastomosis is the preferred urethroplasty technique for radiation-induced urethral stricture. Principles of posterior urethroplasty for trauma may be applied to the treatment of radiation-induced urethral strictures. Chronic management with suprapubic tube is an option based on patient comorbidities and preference.
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The Urologic clinics of North America. 2017 Feb [Epub]
Matthias D Hofer, Joceline S Liu, Allen F Morey
Department of Urology, University of Texas Southwestern, Dallas, TX, USA., Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Department of Urology, University of Texas Southwestern, Dallas, TX, USA. Electronic address: .