Disseminated Mycobacterium tuberculosis Infection Masquerading as Metastasis after Heavy Ion Radiotherapy for Prostate Cancer.

Fluorodeoxyglucose (FDG)-positron emission tomography with computed tomography (FDG-PET/CT) is useful in disease monitoring of malignancies after therapy, while an FDG uptake may also be present in benign diseases. We herein demonstrate a case of disseminated Mycobacterium tuberculosis mimicking systemic metastasis of prostate cancer. This case highlights that clinicians should consider Mycobacterium tuberculosis in patients with prostate cancer who demonstrate multifocal FDG uptakes masquerading as metastasis, even when the chest photographs reveal a normal appearance and a sputum examination demonstrates negative results. An invasive surgical biopsy may be required and a pathological analysis would be critical in the diagnosis of Mycobacterium tuberculosis.

Internal medicine (Tokyo, Japan). 2016 Nov 15 [Epub]

Masaru Ando, Yutaka Mukai, Ryo-Ichi Ushijima, Yoshiyuki Shioyama, Kenji Umeki, Fumito Okada, Shin-Ichi Nureki, Hiromitsu Mimata, Jun-Ichi Kadota

Department of Respiratory Medicine and Infectious Diseases, Oita University Faculty of Medicine, Japan.