Molecular signature to risk-stratify prostate cancer of intermediate risk.

A new 30-gene signature has been described that separates prostate cancers of Gleason score {less than or equal to} 6 from those of Gleason score {greater than or equal to} 8. It provides independent prognostic information for prostate cancers of intermediate risk (Gleason score of 7) which has the potential to stratify these patients into different risk groups.

Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Nov 01 [Epub ahead of print]

Yu Yin, Qingfu Zhang, Hong Zhang, Yiping He, Jiaoti Huang

Anhui Medical University., China Medical University., Duke University., Department of Pathology, Duke University., Department of Pathology, Duke University School of Medicine .