Pituitary apoplexy is a rare complication of the initial administration of leuprolide acetate.
The authors present the case of a 63-year-old man who experienced headache, blurred vision, and loss of consciousness following initial leuprolide treatment for prostate carcinoma. Neuroimaging demonstrated pituitary hemorrhage.
Clinicians should be aware of this rare but known complication of leuprolide injection so that prompt diagnosis and treatment initiation occur in patients with leuprolide-associated pituitary apoplexy.
World neurosurgery. 2016 Aug 29 [Epub ahead of print]
Andrew J Fabiano, Saby George
Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, New York USA; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York USA. Electronic address: ., Department of Medical Oncology, Roswell Park Cancer Institute, Buffalo, New York USA; Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York; Buffalo, New York USA.