Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy.

Cases of synchronous prostate and colorectal adenocarcinomas have been sporadically reported. There are case reports on patients with synchronous prostate and rectal cancers treated with external beam radiotherapy alone or combined with high-dose rate brachytherapy boost to the prostate. Here, we illustrate a patient with synchronous prostate and rectal cancers treated using the volumetric arc therapy (VMAT) technique. The patient was treated with radical radiotherapy to 50.4 Gy in 28 fractions to the pelvis, incorporating the involved internal iliac node and the prostate. A boost of 24 Gy in 12 fractions was delivered to the prostate only, using VMAT. Treatment-related toxicities and follow-up prostate-specific antigen and carcinoembryonic antigen were collected for data analysis. At 12 months, the patient achieved complete response for both rectal and prostate cancers without significant treatment-related toxicities.

Journal of medical radiation sciences. 2015 Oct 10 [Epub]

Sweet Ping Ng, Thu Tran, Philip Moloney, Charlotte Sale, Maitham Mathlum, Grace Ong, Rod Lynch

Department of Radiation OncologyAndrew Love Cancer CentreBarwon HealthGeelongAustralia; Peter MacCallum Cancer CentreMelbourneAustralia., Department of Radiation Oncology Andrew Love Cancer Centre Barwon Health Geelong Australia., Department of Radiation Oncology Andrew Love Cancer Centre Barwon Health Geelong Australia., Department of Radiation Oncology Andrew Love Cancer Centre Barwon Health Geelong Australia., Department of Radiation Oncology Andrew Love Cancer Centre Barwon Health Geelong Australia., Department of Radiation OncologyAndrew Love Cancer CentreBarwon HealthGeelongAustralia; Peter MacCallum Cancer CentreMelbourneAustralia., Department of Radiation Oncology Andrew Love Cancer Centre Barwon Health Geelong Australia.

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