Relationship between CYP17 gene polymorphisms and risk of prostate cancer.

Cytochrome P450 17a-hydroxylase (CYP17) plays a critical role in androgen biosynthesis. Polymorphisms of the CYP17 promoter have been proposed as risk factors for prostate cancer; however, some studies have produced inconclusive or controversial results.

We investigated the relationship between polymorphisms of the CYP17 gene and the risk of prostate cancer. A total of 176 patients with prostate cancer were enrolled in the study, and 168 healthy individuals acted as the control group. The participants were divided into those

Genetics and molecular research : GMR. 2016 Feb 26*** epublish ***

J Song, Z-H Tao, X-Y Liu, S Gong, L Gan

Centre for Preclinical Medicine, SiChuan Medical College, Luzhou, Sichuan, China., Centre for Preclinical Medicine, SiChuan Medical College, Luzhou, Sichuan, China., Centre for Preclinical Medicine, SiChuan Medical College, Luzhou, Sichuan, China., Centre for Preclinical Medicine, SiChuan Medical College, Luzhou, Sichuan, China., Centre for Preclinical Medicine, SiChuan Medical College, Luzhou, Sichuan, China.