Over the past decade, significant data have shown that obese men experience a survival detriment after treatment for prostate cancer. While methods to combat obesity are of utmost importance for the prostate cancer patient, newer data reveal the overall metabolic improvements that accompany increased activity levels and intense exercise beyond weight loss.
Along these lines, a plethora of data have shown improvement in prostate cancer-specific outcomes after treatment accompanied with these activity levels. This review discusses the metabolic mechanisms in which increased activity levels and exercise can help improve both outcomes for men treated for prostate cancer while lowering the side effects of treatment.
Prostate cancer. 2016 Feb 10 [Epub]
Colin E Champ, Lanie Francis, Rainer J Klement, Roger Dickerman, Ryan P Smith
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15215, USA; Department of Integrative Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA., Department of Integrative Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA; Department of Medical Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA., Department of Radiation Oncology, Leopoldina Hospital, 97422 Schweinfurt, Germany., Relentless Fitness, Philadelphia, PA 19106, USA., Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15215, USA.