Incidental Detection of Oxyphilic Papillary Thyroid Carcinoma by 18F-Fluorocholine PET/CT

A 70-year-old man with prostate cancer and increased prostate-specific antigen level of 55 ng/mL underwent staging F-fluorocholine PET/CT, which demonstrated the primary prostate tumor and a focal area corresponding to a 2-cm hypodense nodule in the left thyroid lobe.

Fine-needle aspiration and subsequent total thyroidectomy with central lymph node dissection showed an oxyphilic papillary thyroid carcinoma and a medullary microcarcinoma. Oxyphilic tumors represent a significant proportion of the few case reports of incidental focal thyroid fluorocholine thyroid uptake.

Clinical nuclear medicine. 2016 Feb 24 [Epub ahead of print]

Paul Lalire, Mohamed Zalzali, Christian Garbar, Claire Bruna-Muraille, David Morland

From the *Département de Médecine Nucléaire, and †Département de Biopathologie, Institut Jean Godinot; and ‡Laboratoire de Biophysique, UFR de Médecine-Université de Reims Champagne Ardenne, Reims, France.