We present a systematic review providing estimates of the overall and regional burden of infectious complications following prostate biopsy. A directly standardized prevalence estimate was used because it reflects the burden of disease more explicitly.
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Complications included sepsis, hospitalization, bacteraemia, bacteriuria, and acute urinary retention after biopsy. There were 165 articles, comprising 162 577 patients, included in the final analysis. Our findings demonstrate that transrectal biopsy was associated with a higher burden of hospitalization (1·1% vs. 0·9%) and sepsis (0·8% vs. 0·1%) compared to transperineal biopsy, while acute urinary retention was more prevalent after transperineal than transrectal biopsy (4·2% vs. 0·9%). The differences were statistically non-significant because of large heterogeneity across countries. We also demonstrate and discuss regional variations in complication rates, with Asian studies reporting higher rates of sepsis and hospitalization.
Epidemiology and infection. 2015 Dec 09 [Epub ahead of print]
H Y Bennett, M J Roberts, S A R Doi, R A Gardiner
Centre for Clinical Research,The University of Queensland,Brisbane,Australia. , Centre for Clinical Research,The University of Queensland,Brisbane,Australia. , Research School of Population Health,The Australian National University,Canberra,Australia. , Centre for Clinical Research,The University of Queensland,Brisbane,Australia.