Five-point Likert scaling on MRI predicts clinically significant prostate carcinoma.

To clarify the relationship between the probability of prostate cancer scaled using a 5-point Likert system and the biological characteristics of corresponding tumor foci.

The present study involved 44 patients undergoing 3.

0-Tesla multiparametric MRI before laparoscopic radical prostatectomy. Tracing based on pathological and MRI findings was performed. The relationship between the probability of cancer scaled using the 5-point Likert system and the biological characteristics of corresponding tumor foci was evaluated.

A total of 102 tumor foci were identified histologically from the 44 specimens. Of the 102 tumors, 55 were assigned a score based on MRI findings (score 1: n = 3; score 2: n = 3; score 3: n = 16; score 4: n = 11 score 5: n = 22), while 47 were not pointed out on MRI. The tracing study revealed that the proportion of >0. 5 cm(3) tumors increased according to the upgrade of Likert scores (score 1 or 2: 33 %; score 3: 68. 8 %; score 4 or 5: 90. 9 %, χ (2) test, p < 0. 0001). The proportion with a Gleason score >7 also increased from scale 2 to scale 5 (scale 2: 0 %; scale 3: 56. 3 %; scale 4: 72. 7 %; 5: 90. 9 %, χ (2) test, p = 0. 0001). On using score 3 or higher as the threshold of cancer detection on MRI, the detection rate markedly improved if the tumor volume exceeded 0. 5 cm(3) (

Each Likert scale favobably reflected the corresponding tumor's volume and Gleason score. Our observations show that "score 3 or higher" could be a useful threshold to predict clinically significant carcinoma when considering treatment options.

BMC urology. 2015 Sep 04*** epublish ***

Taisuke Harada, Takashige Abe, Fumi Kato, Ryuji Matsumoto, Hiromi Fujita, Sachiyo Murai, Naoto Miyajima, Kunihiko Tsuchiya, Satoru Maruyama, Kohsuke Kudo, Nobuo Shinohara

Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan. Department of Urology, Hokkaido University Graduate School of Medicine, North-15, West-7, North Ward, Sapporo, 060-8638, Japan. takataka@rf6. so-net. ne. jp. , Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan. fumi-k@zg7. so-net. ne. jp. , Department of Urology, Hokkaido University Graduate School of Medicine, North-15, West-7, North Ward, Sapporo, 060-8638, Japan. ryu-matsumoto@amber. plala. or. jp. , Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan. hiris@wb4. so-net. ne. jp. , Department of Urology, Hokkaido University Graduate School of Medicine, North-15, West-7, North Ward, Sapporo, 060-8638, Japan. sa0034@med. hokudai. ac. jp. , Department of Urology, Hokkaido University Graduate School of Medicine, North-15, West-7, North Ward, Sapporo, 060-8638, Japan. naoto_mi@yb3. so-net. ne. jp. , Department of Urology, Hokkaido University Graduate School of Medicine, North-15, West-7, North Ward, Sapporo, 060-8638, Japan. kunihiko.  Department of Urology, Hokkaido University Graduate School of Medicine, North-15, West-7, North Ward, Sapporo, 060-8638, Japan. maruyama_satoru@ybb. ne. jp. , Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan. kkudo@huhp. hokudai. ac. jp. , Department of Urology, Hokkaido University Graduate School of Medicine, North-15, West-7, North Ward, Sapporo, 060-8638, Japan. 

PubMed    Full Text Article

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