Urinary tract symptoms and erectile function in patients at risk of prostate cancer - Abstract

INTRODUCTION AND OBJECTIVE: We estimate that more tan 63000 prostate biopsies are performed in our country each year.

There are no functional status data of those patients and if there is a relationship between biopsy result and functional status. In order to solve that question we have performed this study.

MATERIAL AND METHOD: 1,128 prostate biopsies were included. Patients fill in the IPSS, IIEF-5 and ICIQ-SF questionnaires before the prostate biopsy was performed. A prospective data collection of clinical, pathological and questionnaires results was done. A descriptive analysis was carried out. IPSS and IIEF-5 results were categorized. Results were compared depending on the biopsy result. In the subgroup of patients with prostate cancer, questionnaires results were stratify according to the clinical risk group.

RESULTS: The mean age of the sample was 65. Prostate cancer detection rate was 32,71%, 52,2% of the sample had mild lower urinary tract symptoms (LUTS) and 13,4% had severe LUTS at the time of the biopsy. Regarding the impact of LUTS on quality of life (QOL), only 12,6% showed a perfect QOL. More than 50 percent of patients suffered from some degree of erectile dysfunction at the time of the biopsy. According to ICIQ-SF, 24% of the sample experienced some kind of urinary incontinence, although it is true that most of them classified it as small amount. Patients with a positive biopsy had a lower IPSS and IIEF-5 average score. There were no differences in the prostate cancer detection rate stratified by the severity of LUTS.

CONCLUSIONS: Patients undergoing prostate biopsy have, with a high probability, LUTS. Approximately 50% suffer from some degree of erectile dysfunction and 24% had some kind of urinary leakage.

Written by:
Ramírez-Backhaus M, González-Tampán J, Ortiz-Rodríguez IM, Gómez-Ferrer Á, Rubio-Briones J, Collado-Serra A, Calatrava A, Rodríguez-Torreblanca C, Solsona-Narbón E.   Are you the author?
Servicio de Urología, Fundación Instituto Valenciano de Urología (FIVO), Valencia, España; Departamento de Estadística e Investigación Operativa, Facultad de Matemáticas, Universidad de Almería, Almería, España; Servicio de Anatomía Patológica, FIVO, Valencia, España.  

Reference: Actas Urol Esp. 2015 Feb 19. pii: S0210-4806(14)00374-X.
doi: 10.1016/j.acuro.2014.10.005

PubMed Abstract
PMID: 25704504

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