Cutaneous metastasis of prostate carcinoma treated with radiotherapy: A case presentation - Abstract

BACKGROUND: Prostate cancer is a commonly diagnosed and treated malignancy, although it rarely presents with cutaneous metastases.

In this case presentation, we describe the diagnosis and treatment with radiotherapy of a patient who presented with cutaneous metastases on his chest wall secondary to prostate cancer.

CASE PRESENTATION: In 2006, a 73-year-old Caucasian gentleman with metastatic castration resistant prostate cancer treated with mitoxantrone and prednisolone presented with cutaneous nodules on his chest wall. A punch biopsy diagnosed cutaneous metastases, with histological confirmation with positive staining for cytokeratin, PSA (prostate specific antigen) and PAP (prostatic acid phosphatise). Systemic treatment was ceased due to progressive disease; radiotherapy was used to treat these nodules with a durable clinical response. The patient died five months after initial diagnosis of cutaneous metastases.

CONCLUSIONS: In this report, a rare metastatic manifestation of a common malignancy is presented. Whilst dermal metastases carries a poor prognosis from reported literature, this is the first report of radiotherapy providing a durable clinical response with relief from bleeding and pain.

Written by:
Mak G, Chin M, Nahar N, De Souza P.   Are you the author?
Prince of Wales Hospital; Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.  

Reference: BMC Res Notes. 2014 Aug 8;7:505.
doi: 10.1186/1756-0500-7-505


PubMed Abstract
PMID: 25103825

UroToday.com Prostate Cancer Section

 

 

 

 

E-Newsletters

Newsletter subscription

Free Daily and Weekly newsletters offered by content of interest

The fields of GU Oncology and Urology are rapidly advancing. Sign up today for articles, videos, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.

Subscribe