Cancers prone to spread to bone include prostate, lung, kidney, breast and thyroid cancers.
While bone scanner has been widely used in the past decades, PET-based imaging modalities are increasingly used. Current modalities of PET imaging of bone metastases include tumor and inflammatory targeting with FDG-PET, bone imaging with NaF-PET, and direct cancer-specific markers such as FDOPA-PET or PET using choline. The cancer-specific metastatic patterns and the relative prognosis conferred by osseous metastases (versus visceral metastases) may determine the need for bone scan, FDG-PET for the detection of bone metastases. Because some cancers have a mixed skeletal and visceral, cocktails PET radiopharmaceuticals may also be discussed in the future. The cancer-specific context and performances of bone scan and PET imaging are discussed.
Written by:
Ouvrier MJ, Vignot S, Thariat J. Are you the author?
Centre Antoine-Lacassagne, médecine nucléaire, 33, avenue de Valombrose, 06136 Nice cedex, France.
Reference: Bull Cancer. 2013 Oct 23. Epub ahead of print.
PubMed Abstract
PMID: 24153039
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