AUA 2012 - Differences In perioperative outcomes between African American and Caucasian patients after radical prostatectomy - Session Highlights

ATLANTA, GA USA (UroToday) - In this analysis, the authors reviewed outcomes of radical prostatectomies performed between 2001 - 2007 from the Nationwide Inpatient Sample (NIS) database to assess outcome differences between Caucasian and African American patients.

Five short-term RP outcomes were assessed, including the rates of blood transfusions, prolonged length of stay, as well as intraoperative and postoperative complications, stratified according to race. Multivariable logistic regression analyses of propensity score matched populations further adjusted for confounding variables.

They found that overall, 7,408 AA (12.6%) and 51,319 Caucasian (87.4%) patients were identified. Significantly higher rates were recorded in AA men for blood transfusions (9.0 vs. 6.0%, p<0.001), intraoperative complications (1.7 vs. 1.3%, p=0.003) and length of hospital stay in excess of three days (28.7 vs. 20.9%, p<0.001). Moreover, higher rates of overall postoperative complications were recorded in AA men (13.0 vs. 10.3%, p<0.001). Multivariable analyses revealed that relative to Caucasian patients, AA patients undergoing RP were more likely to receive a blood transfusion (OR=1.54, p<0.001), to experience an intraoperative (OR=1.37, p=0.003) and postoperative (OR=1.29, p<0.001) complication and to be hospitalized for more than 3 days following surgery (OR=1.56, p<0.001).

African American prostate cancer patients who underwent RP were associated with worse outcomes than Caucasian prostate cancer patients who also underwent RP. There may be explanations for these findings, including disease characteristics and variations in anatomy, however these data also require consideration to differences in levels of care for African American men versus Caucasian men.


Presented by Quoc-Dien Trinh, Jan Schmitges, Maxine Sun, Jesse D Sammon, Khurshid R Ghani, Wooju Jeong, Marco Bianchi, Jay Jhaveri, Paul Perrotte, James O Peabody, Mani Menon, and Pierre I Karakiewicz at the American Urological Association (AUA) Annual Meeting - May 19 - 23, 2012 - Georgia World Congress Center - Atlanta, GA USA

View full AUA Coverage