Ethnic differences in prostate cancer - Abstract

Department of Urology, St Bartholomew's hospital, Barts and The London NHS Trust, West Smithfield, London EC1A 7BE, UK.

Department of Urology, Newham University Hospita lNHS Trust, Glen Road, London E13 8SL, UK.



It is recognised that the risk of prostate cancer is higher in black men than in white men worldwide. Recent studies suggest that a number of genetic mutations in black men predispose them to this disease; hence, race as well as environmental factors such as diet and migration are thought to be the determining factors.

This review compares data from the United States (US), which suggest that African-American men have a 60% higher risk for developing prostate cancer with poorer prognosis in comparison with their white counterparts, with similar studies carried out in the United Kingdom (UK) and also in African and Caribbean countries.

Studies from the United States and the United Kingdom came to significantly different conclusions, and this has implications for policy development, awareness raising among black men in each country and clinical practice.

Written by:
Kheirandish P, Chinegwundoh F.   Are you the author?

Reference: Br J Cancer. 2011 Aug 9;105(4):481-5.
doi: 10.1038/bjc.2011.273

PubMed Abstract
PMID: 21829203 Prostate Cancer Section