EAU 2011 - Impact of surgical technique (open vs. laparoscopic vs. robotic-assisted) on pathological and biochemical outcomes following radical prostatectomy: An analysis using propensity score matching - Session Highlights

VIENNA, AUSTRIA (UroToday.com) - This study sought to compare outcomes of retropubic (RRP), laparoscopic (LRP), and robotic assisted radical prostatectomy (RARP) in a matched fashion with respect to pathological and biochemical outcomes.

A total of 522 consecutive patients who underwent RARP between 2003 and 2008 were matched by propensity scoring on the basis of patient age, race, preoperative PSA, biopsy Gleason score, and clinical stage to an equal number of patients who underwent LRP and RRP. The three surgical approaches were compared regarding pathological and biochemical outcomes.

Positive surgical margin rates were overall lower among patients who underwent RRP (14.4%) and LRP (13.0%) compared to patients who underwent RARP (19.5%) (p = 0.010). However, there were no statistically significant differences in positive margin rates between the three surgical techniques for pT2 disease (p = 0.264). They performed a multivariate logistic regression analysis and found surgical technique (p = 0.016), biopsy Gleason score (p < 0.001) and preoperative PSA (p < 0.001) predictive of positive surgical margins. Kaplan-Meier analysis did not show any statistically significant differences with respect to biochemical recurrence for the three surgical groups.


Presented by Ahmed Magheli, MD, et al. at the 26th Annual European Association of Urology (EAU) Congress - March 18 - 21, 2011 - Austria Centre Vienna, Vienna, Austria


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