Department of Neurosciences, Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, Suite 3336, La Jolla, CA, 92093-0819, USA.
Prostate cancer is rarely associated with leptomeningeal metastasis. An 87-year-old man with a history of prostate cancer presented with leptomeningeal metastasis. He received hormonal therapy with leuprolide. Subsequently, he achieved an impressive response, indicated by a constant fall in his PSA levels and by the stabilization of leptomeningeal disease and clinical improvement. Hormonal therapy may be effective in inducing remission in hormone-sensitive prostate cancer with leptomeningeal metastasis.
Zhang M, Mahta A, Kim RY, Akar S, Kesari S. Are you the author?
Reference: Med Oncol. 2011 Mar 20. Epub ahead of print.