To elucidate regional trends of infectious complications following transrectal ultrasound prostate biopsy (TRUS-PB) from a national, privately-insured database.
Using Market Scan, we identified all men who underwent TRUS-PB from 2010 to 2015. Infectious complications (UTI, prostatitis, sepsis) occurring 30 days after the prostate biopsy from emergency room (ER) visits or hospital admissions constituted the primary outcomes. We analyzed unadjusted and adjusted rates of infectious complications from ER visits and hospital admissions per 100 prostate biopsies by state. Multivariable logistic regression analyses were used to identify patient covariates associated with infectious complications.
During the study interval, we identified 193,490 patients who underwent TRUS-PB. The mean age was 57.6 years (SD: 5.0). Over time the unadjusted national rates of infectious complications remained similar from 0.4 ER visits per 100 prostate biopsies in 2010 to 0.2 in 2015 (p=0.83), and 1.2 hospital admissions per 100 prostate biopsies in 2010 to 1.1 in 2015 (p=0.58). Connecticut had the lowest unadjusted infectious complication rate per 100 biopsies at 0.64, whereas West Virginia had the highest at 2.34. Multivariable analysis revealed higher Elixhauser status and patient age were associated with higher odds of infectious complications (p<0.05).
While rates of infectious complications attributable to prostate biopsies remain relatively stable, significant variation exists at the state level regarding this adverse outcome.
Urology. 2022 Jul 06 [Epub ahead of print]
Jeffrey C Morrison, Anessa Sax-Bolder, Boris Gershman, Badrinath Konety, Peter E Clark, Christopher M Gonzalez, Michael R Bronsert, Granville Lloyd, Rodrigo Rodrigues Pessoa, Eric Ballon-Landa, Simon P Kim
University of Colorado Anschutz Medical Center, Division of Urology, Aurora, Colorado., Beth Israel Deaconess Medical Center, Division of Urologic Surgery, Boston, Massachusetts., Rush Medical College, Division of Urology, Chicago, Illinois., Atrium Health,Department of Urology, Charlotte, NC., Loyola University Medical Center, Department of Urology, Maywood, Illinois., University of Colorado Anschutz Medical Center, Division of Urology, Aurora, Colorado; Adult and Child Consortium for Health Outcomes Research and Delivery Science, Aurora, Colorado., University of Colorado Anschutz Medical Center, Division of Urology, Aurora, Colorado; Rocky Mountain Regional Veterans Hospital; Aurora, Colorado., University of Colorado Anschutz Medical Center, Division of Urology, Aurora, Colorado. Electronic address: .