- Advanced prostate cancer is a highly stressful situation for patients and spouses.
- Spouses are often involved in decision making about prostate cancer treatment.
- Couples agree on either quality of life or life expectancy as the goal of therapy.
- Deteriorations in emotional control and motivation were most frequently reported.
- Spouses adapt their treatment goals to the disease situation.
The aim of this study was to evaluate the role of spouses and the relevance of quality of life (QoL) and life expectancy (LE) in the treatment decision-making process of patients with advanced prostate cancer (CaP).
We also addressed the role of possible mental deterioration, partnership quality, QoL, distress, anxiety, and depression in patients and their spouses.
This was a cross-sectional non-interventional explorative study. We administered questionnaires to 96 patients with advanced CaPand their spouses. Both patients and their spouses were asked about the influence of the spouses on treatment decision making, if they prefer quality of life or life expectancy as main goal of treatment and the perceived deterioration of the patients' mental abilities. Additional questionnaires were used to assess medical history, partnership, global quality of life, distress, depression, and anxiety. We performed statistical tests to compare patients with spouses and correlations to detect associations between variables.
The spouses (65 ± 9 years) were significantly younger than the patients (69 ± 9 years). Ninety-five percent of the patients and 91% of the spouses reported that the spouses were involved in making treatment decisions. There was a high similarity within couples with regard to their preference for QoL or LE during treatment. Between couples, this preference differed markedly. Emotional control and motivation were the areas most commonly reported to have deteriorated among patients' mental abilities. The quality of the partnership was rated as being higher than average by both partners. Among the spouses, the quality of partnership correlated significantly with the preference for LE with regard to treatment decision making. Patients and spouses reported high psychological burdens in all areas, with higher levels of distress and anxiety in spouses (P< 0.01). Reduced quality of life and greater distress, depression, and anxiety were significantly correlated with the amount of deterioration of the patients' mental abilities.
Spouses of patients with advanced CaP seem to respond to different aspects of the disease by adjusting both their involvement in treatment decision making and their preferred goal of treatment. Due to mental deterioration in the patients and pronounced anxiety in their spouses, we suggest that it is important for the attending physician to provide detailed information and support to both partners. Overall, the high-stress situation seems to affect both partners to similar degrees.
Urologic oncology. 2021 Aug 14 [Epub]
Andreas Ihrig, Tobias Hanslmeier, Carsten Grüllich, Stefanie Zschäbitz, Johannes Huber, Anja Greinacher, Christina Sauer, Hans-Christoph Friederich, Imad Maatouk
Division of Psycho-oncology, Department of General Internal and Psychosomatic Medicine, University Hospital Heidelberg, Germany. Electronic address: ., Division of Psycho-oncology, Department of General Internal and Psychosomatic Medicine, University Hospital Heidelberg, Germany., Department of Medical Oncology, National Centre for Tumour Diseases (NCT), University Hospital Heidelberg, Germany; Department of Urology, Medical Faculty Carl Gustav Carus, TU Dresden, Germany., Department of Medical Oncology, National Centre for Tumour Diseases (NCT), University Hospital Heidelberg, Germany., Department of Urology, Medical Faculty Carl Gustav Carus, TU Dresden, Germany., Division of Psycho-oncology, Department of General Internal and Psychosomatic Medicine, University Hospital Heidelberg, Germany; Psycho-oncology Service, National Centre for Tumour Diseases (NCT), University Hospital Heidelberg, Germany., Division of Psycho-oncology, Department of General Internal and Psychosomatic Medicine, University Hospital Heidelberg, Germany; Psycho-oncology Service, National Centre for Tumour Diseases (NCT), University Hospital Heidelberg, Germany; Section of Psychosomatic Medicine, Psychotherapy and Psychooncology, Department of Internal Medicine II, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany.