To examine the time dependent rates of urinary continence (UC) following open retropubic radical prostatectomy (ORRP).
1,995 men undergoing RP were enrolled in a prospective, longitudinal outcomes study. The University of California, Los Angeles-Prostate Cancer Index Urinary Function Index (UCLA-PCI-UFS) was administered at baseline, 3, 6, 12, 24, 96, 120, and 180 months post-ORRP. Urinary continence was defined by <1 pad in 24 hours. Two multiple regression models were used to evaluate the association of time since ORRP with UCLA-PCI-UFI score and UC.
The decrease in UC rates between baseline and 15 years (99.6% vs. 87.2%, p<0.001) and 2 and 15 years (95.3% vs. 87.2%, p=0.021) were statistically significant. UC rates were consistently higher in the younger group at all time points.
A significant decrease in UC rates was observed between baseline to 2 years and 2 to 15 years for the entire cohort. UC rates for age-matched men in the general population followed longitudinally for 15 years are comparable to our study population suggesting that while ORRP causes primarily sphincteric urinary incontinence, it may be protective for subsequent BPH mediated urinary incontinence.
The Journal of urology. 2018 May 07 [Epub ahead of print]
Alex J Xu, Glen B Taksler, Elton Llukani, Herbert Lepor
New York University School of Medicine, New York, NY 10016., Medicine Institute, Cleveland Clinic, Cleveland, OH, 44195., Department of Urology, New York University School of Medicine, New York, NY 10016., Department of Urology, New York University School of Medicine, New York, NY 10016. Electronic address: .