Urinary bladder stone associated with seminal vesicle and prostate infection in a Copenhagen rat

We report a very rare case of urinary bladder stone in a laboratory rat, which was associated with severe prostatitis and seminal vesiculitis. Importantly, the histopathological analysis revealed the rare variety of keratinizing desquamative squamous metaplasia of bladder, prostate, and seminal vesicle epithelium. Immunohistochemistry for alpha smooth muscle actin protein and aniline blue staining for collagen clearly showed interstitial prostate fibrosis. The detail information about these findings and subsequent discussion are provided here.

Journal of natural science, biology, and medicine. 0000 [Epub]

Shantibhusan Senapati, Sujit Suklabaidya, Hrudananda Mallik, Sabyasachi Panda, Datteswar Hota, Manas R Baisakh

Department of Translational Research and Technology Development, Institute of Life Sciences, Tumor Microenvironment and Animal Models Lab, Bhubaneswar, India., Department of Translational Research and Technology Development, Institute of Life Sciences, Tumor Microenvironment and Animal Models Lab, Bhubaneswar, India; Department of Urology, Manipal University, Manipal, Karnataka, India., Department of Translational Research and Technology Development, Institute of Life Sciences, Tumor Microenvironment and Animal Models Lab, Bhubaneswar, India., Department of Urology, SCB Medical College, Cuttack, Odisha, India., Department of Urology, SCB Medical College, Cuttack, Odisha, India., Department of Pathology, Apollo Hospital, Bhubaneswar, Odisha, India.

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