The Role of Therapeutic Layering in Optimizing Treatment for Patients with Castration-Resistant Prostate Cancer (RADAR II)

The objective is to offer recommendations on identification of disease progression, treatment management strategies, and suggestions on timing of initiating and discontinuing specific CRPC treatments.
The RADAR II [Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence] Working Group convened to provide guidance on sequencing, combination, or layering of approved treatments for mCRPC based on available data and clinical experience.

A consensus was developed to address important questions on mCRPC patient management.

In the absence of large scale clinical trials, the Working Group recommends that patients may best be managed with a layered approach of approved therapies with unique or complimentary mechanisms of action.  Urology (2017), 10.1016/j.urology.2016.12.033.

E. David Crawford, Daniel P. Petrylak, Neal Shore, Fred Saad, Susan F. Slovin, Nicholas J. Vogelzang, Thomas E. Keane, Phillip J. Koo, Leonard G. Gomella, Joe M. O'Sullivan, Bertrand Tombal, Raoul S. Concepcion, Paul Sieber, Nelson N. Stone, Steven E. Finkelstein, Evan Y. Yu.

More on the Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence] Working Group
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Watch video with  E. David Crawford and Philip Koo on -
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