Development and Validation of the Korean Version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Patients with Non-muscle invasive bladder Cancer - EORTC QLQ-NMIBC24

We aimed to evaluate psychometric properties of the Korean version of the EORTC QLQ-NMIBC24 when applied to Korean non-muscle invasive bladder cancer (NMIBC) patients.

A total of 249 patients who underwent curative transurethral resection of bladder tumor (TURBT) for primary or recurrent NMIBC were asked to complete the Korean version of EORTC QLQ-C30 and NMIBC24 questionnaires three times (preoperative, post-TURBT 3 months and 6 months). Linguistic validation and psychometric evaluation of the questionnaire was conducted.

Multitrait scaling analysis confirmed satisfactory construct validity in 5 scales except the malaise scale. Internal consistency was good (Cronbach's alpha ≥ 0.70) for the 5 scales except the malaise scale at the all 3 time points. Known-group comparison analyses showed better quality-of-life (QOL) scores in patients with higher performance status as expected, and better sexual function in men than women (p < 0.05). Most of the scales had low correlations (< 0.40) with the scales in QLQ-C30 showing divergent validity, except for malaise scale which showed higher correlations (0.42 to 0.60). Responsiveness to change was consistent with clinical implications over time after TURBT.

The Korean version of the EORTC QLQ-NMIBC24 has good reliability and cross-cultural validity for measuring various QOL aspects that can be self-administered to Korean NMIBC patients undergoing TURBT.

Cancer research and treatment : official journal of Korean Cancer Association. 2017 Mar 10 [Epub ahead of print]

Jinsung Park, Dong Wook Shin, Tae-Hwan Kim, Seung Il Jung, Jong Kil Nam, Seung Chol Park, Sungwoo Hong, Jae Hung Jung, Hong-Wook Kim, Won Tae Kim

Department of Urology, Eulji University Hospital, Eulji University School of Medicine, Daejoen, Korea., Department of Family Medicine, Seoul National University Hospital, Seoul, Korea., Department of Urology, Kyungpook National University School of Medicine, Daegu, Korea., Department of Urology, Chonnam National University Medical School, Gwangju, Korea., Department of Urology, Pusan National University Yangsan Hospital, Yangsan, Korea., Department of Urology, Wonkwang University School of Medicine, Iksan, Korea., Department of Urology, Dankook University College of Medicine, Cheonan, Korea., Department of Urology, Yonsei University Wonju College of Medicine, Wonju, Korea., Department of Urology, Konyang University College of Medicine, Daejeon, Korea., Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Korea.