Patients with bladder cancer (BC) have been found to have worse experiences than those with other cancers which may partly be due to impact on quality of life. Currently, little is known about the impact of physical activity (PA) on BC outcomes. This scoping review aims to identify what interventions are available, their reported efficacy and feasibility, and a description of potential underlying biological mechanisms for their effects.
Preferred Reporting Items for Systematic Reviews and Meta-Analyses Scoping Review (ScR) guidelines and the Levac methodology framework will be followed/used. Electronic databases will be searched (MEDLINE, EMBASE, the Cochrane Library, PsycInfo and Health, OpenGray). Two independent reviewers will screen all abstracts and titles and during a second stage and full-text publications for inclusion. All studies describing PA (as an existing lifestyle or as part of an intervention programme) during BC management will be included. Study characteristics will be recorded; qualitative data will be extracted and evaluated using the Donabedian framework. Quantitative data will be extracted and summarised. A further consultation step will be carried out with patients, their family members and healthcare professionals.
Results will be disseminated through a peer-reviewed publication. Through the consultation step, we will ensure that findings will reach a wide audience and recommendations can be made for future development of PA interventions for patients with BC. Data used will be from publicly available secondary sources, and the consultation step will be carried out as part of patient and public involvement so this study does not require ethical review.
BMJ open. 2019 Nov 12*** epublish ***
Sneha Mehrotra, Megan Rowland, Hanyu Zhang, Beth Russell, Louis Fox, Katharina Beyer, Elke Rammant, Nicola Peat, Mieke Van Hemelrijck, Cecilia Bosco
Translational Oncology and Urology Research, King's College London, London, UK., Human structure and repair, Ghent University, Ghent, Belgium., Physiotherapy Dept - Guy's Cancer Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Translational Oncology and Urology Research, King's College London, London, UK .