Sodium restriction improves nocturia in patients at a cardiology clinic.

This study aims to determine whether dietary sodium restriction counseling decreases nocturnal voiding frequency in cardiology patients with concomitant nocturia. Patients who had established care at a cardiology clinic from 2015 to 2018 reporting ≥1 average nocturnal void(s) underwent a comprehensive sodium intake interview by their cardiologist, who provided them with individualized strategies for dietary sodium reduction and assessed adherence at follow-up. Average nocturnal voiding frequency and dietary adherence were documented in the medical record. A nocturia database was compiled for retrospective analysis. A total of 74 patients were included. Patients considered to be adherent with dietary sodium restriction at follow-up (n = 56) demonstrated a decrease in median nocturia frequency (2.5 [2.3-3.0] vs 1.0 [1.0-2.0] voids, P < .001). Among nonadherent patients (n = 18), median nocturia frequency did not significantly change from baseline to follow-up (2.0 [1.5-3.8] vs 2.0 [1.5-4.8] voids, P = .423). Median changes were significantly different between the adherent and nonadherent groups (P < .001). Examination of second follow-up available from 37 patients showed a continued effect. In conclusion, adherence with dietary sodium counseling appears to improve nocturia. Accordingly, dietary modification may represent an important adjunct therapy to lifestyle and pharmacologic interventions for decreasing nocturia frequency. Reduction in nocturnal voiding frequency may also reflect an additional benefit of dietary sodium restriction in accordance with best practice standards for cardiovascular disease.

Journal of clinical hypertension (Greenwich, Conn.). 2020 Feb 12 [Epub ahead of print]

Thomas F Monaghan, Kyle P Michelson, Zhan D Wu, Fred Gong, Christina W Agudelo, Christopher D George, Upeksha S Alwis, Matthew R Epstein, Pakinam Mekki, Viktor X Flores, Donald L Bliwise, Karel Everaert, Johan Vande Walle, Jeffrey P Weiss, Jason M Lazar

Department of Urology, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA., Department of Urology, Ghent University Hospital, Ghent, Belgium., Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA., Department of Pediatric Nephrology, Ghent University Hospital, Ghent, Belgium., Division of Cardiovascular Medicine, Department of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.