Impact of Cystectomy with Urinary Diversion upon Tracked Receipt of Opioid Prescriptions among Patients with Interstitial Cystitis/Bladder Pain Syndrome

To compare opioid requirements before and after cystectomy for end stage Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) using a statewide tracking system.

Narcotic prescriptions were captured using the North Carolina Controlled Substance Reporting System for patients at a single institute undergoing cystectomy with urinary diversion (CWUD) for refractory, end stage IC/BPS between 2010-2017. Values were documented for the year before and the year after surgery (excluding 30 days postoperatively to account for surgical pain) and converted to Morphine Equivalents (ME). Values were compared using the Student's T-test.

Following CWUD, there was a mean decrease in opioid receipt per patient of 6,535 ME/year (p = 0.321). 8/26 (31%) had not filled any opiate prescriptions for the preceding 3 months at time of manuscript.

In certain patients with end stage, refractory IC/BPS, CWUD can help reduce opioid requirements.

Urology. 2017 Nov 17 [Epub ahead of print]

David S Koslov, Fernandino Vilson, Marc Colaco, Ryan P Terlecki, Robert J Evans