PURPOSE:To evaluate the relationship between pathologically proven prostatic inflammation (PI) and re-operation rates due to urethral stricture (US) or bladder neck contracture (BNC) after transurethral resection of prostate (TUR-P).
MATERIALS AND METHODS:We have retrospectively reviewed the data of 917 consecutive TUR-P cases. Eligible patients (n = 276) were grouped with respect to presence of PI on TUR-P pathology; Group1: PI (+) (n = 67, 24.3%), and Group2: PI (-) (n = 209, 75.7%). The "re-operation" was defined as internal urethrotomy or bladder neck resection performed for BNC or US. Groups were compared with respect to descriptive data and need for re-operation. Logistic regression analysis was performed to estimate the independent risk factors for the development of BNC and US. P values under 0.05 were considered significant.
RESULTS:Of the patients, 38 (13.8%) needed re-operation while 238 (86.2%) did not. The re-operation rate in Group1 was significantly higher than Group2 (29.8 vs. 8.6%, P < 0.001). In logistic regression analysis, duration of initial TUR-P and PI were found to be independent risk factors for development of BNC or US after TUR-P.
CONCLUSIONS: Prostatic inflammation on TUR-P pathology is an independent variable affecting the development of US or BNC. Our results should be supported by prospective studies including higher number of patients.
Written by:
Doluoglu OG, Gokkaya CS, Aktas BK, Oztekin CV, Bulut S, Memis A, Cetinkaya M. Are you the author?
Department of Urology, Ankara Numune Education and Research Hospital, Ulku Mahallesi, Talatpasa Bulvari, Nr: 5, 06100 Altindag, Ankara, Turkey.
Reference: Int Urol Nephrol. 2012 Aug;44(4):1085-90.
doi: 10.1007/s11255-012-0127-y
PubMed Abstract
PMID: 22252218
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