Psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome: A randomized controlled trial

To explore the efficacy of psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome.

A total of 156 patients with category III chronic prostatitis/chronic pelvic pain syndrome were randomly divided into two groups: the control group of 78 patients receiving routine medication; and the intervention group of 78 patients receiving psychological intervention therapy combined with routine medications. Treatment courses were for 3 months. The end-points were the response rate of the National Institutes of Health Chronic Prostatitis Symptom Index, International Index of Erectile Function-5, Self-Rating Anxiety Scale, Self-Rating Depression Scale and expressed prostatic secretion-white blood cells.

After 3 months, the average scores of the National Institutes of Health Chronic Prostatitis Symptom Index decreased to 10.1 ± 5.0 in the control group compared with 14.1 ± 4.9 in the intervention group; thus, significant differences were observed between the two groups in the study (P < 0.001). The average scores of the International Index of Erectile Function-5 were improved in the two groups, but compared with the control group, a more marked improvement was detected in the psychological intervention group, and there was a significant difference between the two groups (P < 0.001). There was significant difference between the two groups in terms of the Self-Rating Anxiety Scale and Self-Rating Depression Scale scores (P < 0.001). Expressed prostatic secretion-white blood cell counts significantly decreased to 4.4 ± 3.5 in the control group compared with 9.8 ± 3.4 in the intervention group (P < 0.001).

Psychological intervention therapy can effectively improve the psychological status and sexual function in patients with category III chronic prostatitis/chronic pelvic pain syndrome than the routine medication.

International journal of urology : official journal of the Japanese Urological Association. 2018 Jun 03 [Epub ahead of print]

Jianxin Wang, Kuixiang Liang, Huijing Sun, Lianpeng Li, Hongcai Wang, Jingyuan Cao

Department of Urology, Taizhou First People's Hospital, Taizhou, China., Department of Obstetrics, Binzhou Medical University Hospital, Binzhou, China., Department of Nursing, Binzhou Polytechnical College, Binzhou, China., Department of Urology, Binzhou Central Hospital, Binzhou, China., Department of Neurology, Binzhou Medical University Hospital, Binzhou, China.