Comparison between AMS 700™ CX and Coloplast™ Titan inflatable penile prosthesis for Peyronie's disease treatment and remodeling: Clinical outcomes and patient satisfaction - Abstract

Introduction: The implantation of inflatable penile prosthesis (IPP) with simultaneous manual penile remodeling allows for men to undergo a single procedure aimed at correcting both the penile deformity/curvature and erectile dysfunction (ED).

Aim: To evaluate the clinical outcomes and patient satisfaction in men with Peyronie's disease (PD) and ED who underwent AMS 700™ CX and the newer Coloplast™ Titan inflatable penile prosthesis (IPP) implant.

Main Outcome Measures: Patient demographics, type of IPP, clinical outcomes, post-implant sexual characteristics, and overall patient satisfaction. Methods.  A single-center retrospective review of clinical database and prospective telephone survey were conducted in all men with PD who underwent IPP between January 2006 and November 2010.

Results: A total of 138 patients with an average age of 57.7 (32 to 80) underwent AMS 700 CX (88 patients) and Coloplast Titans (50 patients) IPP implantation during the 5-year period. The majority of patients (91%) had only one IPP implantation. The IPP clinical outcomes include eight (6%) revision surgery for device malfunction and three (2%) device explantation for prosthesis infection. While there was no statistically significance in device survival between the two devices, the trend favored AMS 700 CX over Titan (5-year Kaplan-Meier estimates of mechanical survival were 91% vs. 87%, P > 0.05) and both IPPs provided similar penile straightening without the need for revision surgery. Most men (79%) reported great satisfaction following CX or Titan implants with greater than two thirds of men reported greater self-confidence and 82% of patients would undergo the same operation again.

Conclusions: AMS 700™ CX and Coloplast™ Titan IPP implantation and penile remodeling appeared to provide permanent penile straightening and high patient satisfaction without an increase risk of revision surgery.

Written by:
Chung E, Solomon M, Deyoung L, Brock GB.   Are you the author?
Division of Urology, St Joseph's Health Care, London, ON, Canada; Department of Urology, Princess Alexandra Hospital, Brisbane, QLD, Australia.

Reference: J Sex Med. 2012 Dec 4. Epub ahead of print.
doi: 10.1111/jsm.12009

PubMed Abstract
PMID: 23210973 Peyronie's Section