Peyronie's Disease

Home modeling after penile prosthesis implantation in the management of residual curvature in Peyronie's disease.

The aim of this study was to study the clinical effectiveness of a structured home modeling (HM) protocol in Peyronie's disease (PD) patients who have residual curvature up to 45° after inflatable penile prosthesis (PP) placement.

A decade of grafting techniques as a sole treatment for Peyronie's disease.

Peyronie's disease (PD) can be a cosmetically and functionally devastating condition. Surgical approaches have been proposed in the chronic stages of PD as plication or plaque incision/excision with grafting to preserve penile size in complex cases.

An Innovative Strategy for Non-Grafting Penile Enlargement: A Novel Paradigm for Tunica Expansion Procedures.

Peyronie's disease, diabetes, trauma, pelvic surgeries, and aging are conditions that promote penile fibrosis and trigger erectile dysfunction associated with penile reduction. These pathologies require an objective preoperative diagnosis and intraoperative management of penile shrinkage.

The Natural History of Peyronie's Disease.

Peyronie's disease (PD), a fibrotic disorder of the tunica albuginea fully described in 1793 by French physician Francois de la Peyronie, is characterized by pain, plaque formation, penile deformity, and ultimately sexual function decline.

Evaluating the Impact of Penile Girth Discrepancy on Patient Bother in Men With Peyronie's Disease: An Observational Study.

Men with Peyronie's disease (PD) may experience penile narrowing. Little data on penile girth changes and their psychosocial impact exist.

To assess girth discrepancy in men with PD and its association with patient bother.

Long-Term Outcomes of Surgery for Peyronie's Disease: Focus on Patient Satisfaction - Beyond the Abstract

While this paper is dedicated to the outcomes of surgery for Peyronie’s disease, it seems that the greatest challenge in the management of this condition lies not in surgical technique, but in patient counseling. The patient may have a minor penile curvature coupled with major psychological problems, which won’t be resolved after surgery that may sometimes become aggravated. It is better to avoid surgery altogether when dealing with penile curvature which doesn’t impede coitus. However, some patients keep insisting on intervention and remain unsatisfied with their results after the surgeon finally yields to their demands. This group of patients, most of them being dysmorphophobic, are very difficult to manage.

Treatment Related Outcomes for Patients with Atypical Peyronie's Disease using Xiaflex Injections.

To evaluate the efficacy and safety of collagenase Clostridium histolyticum (CCH) for the management of penile deformities in patients presenting with different categories of atypical Peyronie's disease (PD).

The relationship between testosterone levels and Peyronie's disease.

Aetiologic and predisposing factors are still controversial about Peyronie's disease (PD). However, it is thought to be the result of connective tissue disorder or healing defect. Androgens are known to affect collagen metabolism and wound healing in the body.

A clinical pathway for the management of Peyronie's disease: integrating clinical guidelines from the International Society of Sexual Medicine, American Urological Association and European Urological Association.

To provide a clinical framework and key guideline statements to assist clinicians in the evidence-based management of Peyronie's disease (PD).

We conducted a review of the published literature relevant to PD management, with an emphasis on published clinical guidelines.

Recent advances in managing Peyronie's disease.

Treating men with Peyronie's disease remains a challenging problem facing clinicians working across urology and sexual medicine fields. Patients can often be left disappointed by current treatment paradigms, and an overall lack of suitable molecular targets has limited the options for novel, effective medical therapy.