Peyronie's Disease

Peyronie's disease (PD) is a fibrotic disorder of the tunica albuginea causing penile curvature and functional impairment. Platelet-rich plasma (PRP) injections have been proposed as a regenerative therapy, but current evidence remains limited and heterogeneous.

Peyronie's disease (PD) is an acquired connective tissue disorder characterized by fibrous plaque formation within the penile tunica albuginea that may be influenced by androgen status.

To evaluate whether baseline testosterone levels and testosterone therapy (TTh) during collagenase clostridium histolyticum (CCH) treatment affect curvature severity and treatment outcomes in men with PD.

Penile curvature due to Peyronie's disease (PD) or congenital penile curvature (CPC) may impair sexual function and quality of life. We aimed to evaluate effectiveness, safety, and patient satisfaction after corporoplasty at a tertiary referral center.

The association between Diabetes Mellitus (DM) and Peyronie's disease (PD), as well as the impact of DM on PD phenotypes, remains not fully elucidated.

To investigate the association between PD and DM and to assess the impact of DM on the clinical phenotype of PD.

Plaque incision and grafting is a well-established treatment for severe or complex Peyronie's disease and preserved erectile function. This retrospective single-centre cohort study evaluated 325 patients undergoing the procedure between 2009 and 2024 at a high-volume centre.

Peyronie's disease (PD) is a condition with significant physical, sexual, and psychological impact that is not fully captured by existing Patient-Reported Outcome (PRO) instruments.

To develop and preliminarily validate the PEYROnie's disease Questionnaire (PEYRO-Q), a novel multidimensional PRO questionnaire designed to provide a comprehensive and inclusive assessment of PD.

Peyronie's disease (PD) research has limitations due to heterogeneity in time of presentation, severity, deformity characteristics, and associated conditions.

To provide further insight into clinical characteristics of patients, PD treatments and patient perceptions of outcomes in clinical practice in Spain.

The relationship between psoriatic arthritis (PsA) and Peyronie's disease (PD) remains poorly understood. PsA is a chronic immune-mediated inflammatory disease, whereas PD is a fibroproliferative disorder of the penile tunica albuginea that leads to penile curvature, pain, and sexual dysfunction.

Penile curvature correction surgeries for Peyronie's disease require a learning curve to acquire confidence and precision in optimally performing the procedures for the patient. Given that these interventions are not frequent in daily practice, surgical simulation with hyperrealistic models can be a tool for correctly and safely acquiring technical skills.

Peyronie's disease (PD) is a connective tissue disorder of the penile tunica albuginea that leads to curvature, deformity, and erectile dysfunction, resulting in significant psychosocial distress.