The Changes of Psychometric Profiles after Medical Treatment of Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia

OBJECTIVE - To investigate the relationship of somatization and depression with the degree of lower urinary tract symptoms suggestive of benign prostate hyperplasia (LUTS/BPH) and changes in psychometric profiles including somatization and depression after treatment of LUTS/BPH.

METHODS - Subjects were evaluated at baseline and at week 12 following routine treatment for LUTS/BPH using the International Prostate Symptom Score (IPSS) to measure the severity of LUTS/BPH, the Overactive Bladder Symptom Score (OABSS) to measure the severity of OAB, the Patient Health Questionnaire-9 (PHQ-9) to assess depression, and the Patient Health Questionnaire-15 (PHQ-15) to evaluate somatization. The correlation of somatization and depression with the degree of LUTS/BPH symptoms at baseline and changes in somatization and depression after LUTS/BPH treatment were assessed using relevant statistical analyses.

RESULTS - One hundred and twenty patients agreed to participate in this study, and 101 (84. 2%) completed the 12-week trial and responded to the study questionnaires. At baseline, total IPSS score was correlated with PHQ-9 (r=0. 475, p=0. 005) and PHQ-15 (r=0. 596, p

CONCLUSIONS - Our preliminary results indicated that severity of LUTS is correlated with severity of somatization and depression. Further, the improvement of LUTS after treatment may have positive impacts on somatization and depression.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. 2015 Dec 31 [Epub]

Kang Jun Cho, Nam Suk Lee, Yong Seok Lee, Woon Jin Jeong, Hong Jin Suh, Joon Chul Kim, Jun Sung Koh

Department of Urology, College of Medicine, The Catholic University of Korea. , Department of Urology, College of Medicine, The Catholic University of Korea. , Department of Urology, College of Medicine, The Catholic University of Korea. , Department of Psychiatry, Seoul Metropolitan Eunpyeong Hospital, Seoul, Korea. , Department of Urology, College of Medicine, The Catholic University of Korea. , Department of Urology, College of Medicine, The Catholic University of Korea. , Department of Urology, College of Medicine, The Catholic University of Korea.

PubMed