Urodynamic characterization of lower urinary tract symptoms in men less than 40 years of age - Abstract

Purpose: Lower urinary tract symptoms (LUTS) in young men are becoming a more recognized urologic issue that can arise from many causes, each with their own management strategy.

The purpose of this study was to determine the rates and types of voiding dysfunction causing LUTS in men under 40 years.

Lower urinary tract symptoms (LUTS) in young men are a urologic issue that can arise from many causes, each with its own management strategy. In this study, we characterized males under the age of 40 using video urodynamic studies. This study presents the findings of 87 men age 40 years or less with chronic LUTS, defined as symptoms persisting for great than 6 months. BOO was the most prominent diagnosis occurring in 48.24 % of our cohort of young men and the second most common diagnosis was dysfunctional voiding...Bilal Chughtai, MD

Methods: Videourodynamic studies (VUDS) of 87 men 40 years of age or less with LUTS for greater than 6 months, performed between July 2004 and June 2012 at Weill Cornell Medical College, were retrospectively analyzed. Patients with culture-proven bacterial prostatitis, symptoms for less than 6 months, a history of neurologic disease, or previous urological surgery affecting voiding function were excluded from the analysis.

Results: The mean age of the patients was 31.84 ± 5.78. There were 37 patients that presented with more than one urinary symptom (42.5 %). The most frequent complaints included: urinary frequency (N = 42, 48.28 %), difficulty with urination (N = 41, 47.13 %), and urinary urgency (N = 21, 24.14 %). The most common urodynamic abnormality was bladder outlet obstruction (BOO) (N = 37, 42.53 %), dysfunctional voiding (N = 25, 28.74 %), detrusor underactivity (N = 10, 11.49 %), and detrusor overactivity (N = 7, 8.05 %). There were no differences seen in AUA symptom and quality of life scores across diagnosis groups.

Conclusions: Lower urinary tract symptoms can present in younger men with a variety of types of voiding dysfunction. This study uses VUDS to show that the most common types of voiding dysfunction in this population with chronic LUTS are BOO followed by dysfunctional voiding.

Written by:
Jamzadeh AE, Xie D, Laudano M, Seklehner S, Elterman DS, Shtromvaser L, Lee R, Kaplan SA, Te AE, Chughtai B.   Are you the author?
James Buchanan Brady Department of Urology, Weill Cornell Medical College of Cornell University, 525 East 68th Street, F9West, Box 261, New York, NY, 10065, USA.

Reference: World J Urol. 2013 Jul 25. Epub ahead of print.
doi: 10.1007/s00345-013-1134-z


PubMed Abstract
PMID: 23884373

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